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Carnitines major role is in allowing the transfer of long-chain fatty acids into the mitochondria, where they are then oxidized for energy

Neuroscience Letters 2003

But studies show they can be taken safely together

was of two vegan families who had been vegan for at least two years and had not regularly received B12 from supplements or fortified foods (Crane, 1998)

Vitamin B12 deficiency is particularly relevant in older patients and in anyone taking metformin concurrently, as metformin is known to reduce B12 absorption