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According to the report of An et al

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[106] A single pound of fat yields approximately 3500 calories of energy (32 000 kJ energy per kilogram of fat), and weight loss is achieved by reducing energy intake, [107] or increasing energy expenditure, thus achieving a negative balance

ChaC1 mRNA expression is upregulated in response to ER stress-inducing agents such as thapsigargin, tunicamycin, and brefeldin A

If the overdose is severe, patients may have a fast heart rate and low blood pressure, and their stomach may be tender when touched

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