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A 2022 systematic review and meta-analysis of fibers impact on constipation concluded that dietary fiber sources can have a significant effect on constipation, especially at higher-than-average doses (adding 10 grams or more per day to your standard intake)

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doi: 10.1111/cei.12566 251 WebbKCTungRWinterfieldLSGottliebABEbyJMHenningSWet al

Wang, H., McGoldrick, L

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Therefore, the implementation of a combined pharmacological therapy acting via different pathways becomes necessary, and its combination with a compound of the sulfonylurea group was along decades the most frequently employed prescription in routine clinical practice