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Adaptation of the human aryl hydrocarbon receptor to sense microbiota-derived indoles

159 Although the mechanism by which cGAS-STING axis activates NLRP3 inflammasome remains unclear, these findings provide new evidence that mtDNA-mediated DAMPs can also mediate inflammasome activation via the cGAS-STING-NLRP3 axis

Convient aux vgtariens et vgtaliens

Targeting ferroptosis in acute kidney injury

Abstract Dopaminylation, the covalent attachment of dopamine to the side chain of glutamine in proteins, represents a newly characterized class of posttranslational modifications

1 Introduction Liver disease represents a major global health challenge with diverse etiologies, including viral infections (hepatitis B and C), alcohol abuse, metabolic disorders (Metabolic Dysfunction-Associated Steatotic Liver Disease, MASLD), drug- and toxin-induced injuries, and autoimmune hepatitis