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According to Sanguigno et al., HDAC9 interacts with hypoxiainducing factor 1 (HIF1) and Sp1, transcriptional activators of the GPX4 and transferrin receptor 1 (TfR1) genes, respectively, in nerve cells exposed to oxygenglucose deprivation/reperfusion (Figure 3C) [90]

Its deficiency, although rare, may present with dermatitis, brittle nails, and hair loss (248)

Introduction The term autism spectrum disorder (ASD) describes a clinical spectrum of neurodevelopment conditions characterized by deficits in social communication and social interaction with restricted, repetitive patterns of behavior, interests, or activities ( Because of the heterogeneity associated with ASD, tremendous efforts have been made to identify underlying mechanisms or markers for this complex set of disorders with limited success ( Figure 1 )

doi: 10.1007/s00405-008-0642-8