The cycle structure exists for a practical reason: continuous stimulation of the same receptor pathways can lead to reduced sensitivity over time, and a rest period allows the system to reset before the next cycle produces full effect
Even though most therapies have no specific length of time to be on treatment, there are some guidelines that we recommend that patients follow
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Nevertheless, this possibility is ruled out by the fact that Ex-4 decreases the expression of CPT1, the rate-limiting enzyme for mitochondrial -oxidation 67