Hyperphosphorylated tau detaches from microtubules, aggregates, and forms paired helical filaments, leading to the collapse of the neuronal transport system and subsequent neurodegeneration (Han et al
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Peptide-bond modified glutathione conjugate analogs modulate GSTpi function in GSH-conjugation, drug sensitivity and JNK signaling
This paradox may be explained by the antioxidant paradox, where excessive scavenging of ROS disrupts their physiological role in capacitation and acrosome reaction (Qamar et al., 2023)
DARU J Pharm Sci
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