10.3252/pso.eu.ILC2022.2022 92 WalczakR.CaroleB.BenoitN.DescampsE.NathalieD.MegnienS.et al (2018)
Its too important and needed better writing
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When expressed in cultured cells, these mutated proteins can slow the dynamics of SGs and other RNP assemblies, leading to persistent TDP43+ granules and/or the formation of rigid, amyloid-like solids reminiscent of those observed in affected tissues of patients with MSP and related disorders ( 26 31 )
Expect recovery changes within 12 weeks
The litigations further allege that manufacturers failed to adequately warn patients and prescribing physicians about potential risks associated with these drugs despite emerging safety reports, adverse event data, and growing medical concern surrounding gastrointestinal and optic nerve injuries