Ethics statement This study was approved by the the Research Ethical Review Committee of Faculty of Medicine and Pharmacy of Oujda, Morocco (Approval code: 02/2023
Key active ingredients include CoQ10 , Alpha Lipoic Acid, Reduced Glutathione, and PQQ
Activation of AMPK prevents the polarization of pro-inflammatory macrophages (M1) triggered by lipopolysaccharide, thereby reducing inflammation and subsequently improving insulin resistance
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In older animals, both high-dose paraxanthine and caffeine (CAF HIGH) produced the most significant improvements, consistent with previous research showing age-related declines in learning and memory acquisition in water maze tests
It is important to note that these side effects are usually mild and do not last long