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All experiments were performed following standardized protocols to minimize variability, and independent validation was conducted for key findings using alternative methods where feasible

However, patients with irritable bowel syndrome or IBD are better off with a low-FODMAP diet, as it can exacerbate disease symptoms due to gas production and stretching of the intestinal lumen [8, 130,131,132]

DSIP was administered intravenously to patients for 5 consecutive days, followed by 5 additional injections every 4872 hours

The frequency, severity and disability of headache were decreased after 3 months

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