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While the expiry of the primary semaglutide patent in many jurisdictions is significant, it does not mean Ozempic is free for generic manufacture worldwide

Novo Nordisk has added ileus to the Postmarketing Experience section of the Wegovy label under Gastrointestinal Disorders. In October 2025, Severe Gastrointestinal Adverse Reactions was added to the WARNING AND PRECAUTIONS section of the label

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Some people experience a genuine semaglutide plateau even with verified pharmaceutical-grade products

Patients who use it may also experience improvements in various health markers, including reduced blood pressure, better blood sugar control, and decreased risk factors for heart disease

The OFA has signaled plans to appeal, with similar litigation ongoing regarding semaglutide, the active ingredient in Ozempic