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This is mechanistically distinct from proton pump inhibitor pharmacology and is part of why the peptide attracts interest as a research tool for ulcer biology and NSAID-induced gastric injury

The brand printed on the label is less informative than the documentation available for the product inside the vial

These adverse effects stem from the entry of the cytoplasmic exonuclease TREX1 into the nucleus, which induces DNA cleavage [195], as well as the translocation of DNA repair factors such as Ku70, Ku80, and BRCA1 to the cytoplasm [190, 194]

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The patient will be at the heart of everything the NHS does

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