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Future success will depend not only on refining therapeutic targets but also on optimizing dosing strategies and establishing reliable, non-invasive biomarkers for senescence, enabling safe, effective, and personalized application in clinical aging medicine

Elife 7, e38472

While mouse studies do not directly translate to humans, the concentration of beta-3 receptors in human visceral fat tissue suggests a similar preferential targeting is plausible

If you notice unexplained weight gain exceeding 23 kg over a short period whilst taking glucosamine, consult your GP to rule out other causes