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When glutathione stores deplete, NAPQI metabolites accumulate unchecked, binding to hepatocyte proteins and triggering cell death

The metabolic changes are measurable in blood work

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This is the first clinical trial to demonstrate that semaglutide may improve liver fibrosis in patients with advanced MASH, including those with compensated cirrhosis, said Rohit Loomba, MD, senior author of the study, gastroenterologist and hepatologist at UC San Diego Health and chief of the Division of Gastroenterology and Hepatology at UC San Diego School of Medicine

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