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Biochem J 1975

In a 2023 randomized trial published in the ClinicalTrials.gov database, participants experienced an average of 1724% total body weight reduction after 48 weeks of treatment

Genetic testing may reveal reduced GLP-1 receptor sensitivity, prompting a switch to tirzepatide or GLP-Squared (dual compound)

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645 Protoplasmic (but not fibrous) astrocytes protect against -synuclein toxicity by removing this latter through endocytosis, 646,647 and hence astrocytic atrophy reduces neuroprotection

It is used in a particular manner: it is chronic kidney disease that has to undergo chronic dialysis