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[10] NF-B is a protein complex that functions as a transcription factor, regulating the expression of genes involved in immune and inflammatory responses

Following FOXO4 displacement, the released p53 undergoes nuclear export and mitochondrial translocation, activating the intrinsic apoptosis pathway via BAX upregulation and BCL-2 downregulation, culminating in caspase-3 cleavage and apoptotic cell death

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