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A new study found that highly purified chondroitin can reduce pain and stiffness and increase function

This suggests a hereditary component

Anti-Inflammatory Effects: Reduces inflammatory markers and attracts immune cells to sites of damage, coordinating the healing response

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Senescent and apoptosis-resistant lung fibroblasts have been shown to contribute to the persistence and progression of fibrosis [15]

Clinical Pathobiochemistry of Vitamin B12