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N Jelovac, P Sikiric, R Rucman, M Petek, D Perovic, A Marovic, T Anic, S Seiwerth, S Mise, B Pigac, B Duplancie, B Turkovic, G Dodig, I Prkacin, D Stancic-Rokotov, I Zoricic, G Aralica, B Sebecic, T Ziger, Z Slobodnjak, The effect of a novel pentadecapeptide BPC 157 on development of tolerance and physical dependence following repeated administration of diazepam

Combining the (KLAKLAK)2 peptide with the CNGRC peptide, an aminopeptidase N-targeting peptide, efficiently inhibited tumor growth by targeting the enzyme present in angiogenic tumor endothelial cells 52

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Yet another aspect of the invention is to provide a method for treating patients not responsive to a maximum recommended dose of a PDE-5 inhibitor, the method including administering both PT-141 and a PDE-5 inhibitor, wherein the PDE-5 inhibitor is administered prior to, at approximately the same time as, or subsequent to administration of PT-141 , and further wherein the dose PT-141 is between about 2.5 mg and about 15 mg

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