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With an increase in calcium oxalate concentration, the expression of p53, ACSL4 and TRC in renal tubular epithelial cells increased, while the expression of SLC7A11 and GPX4 decreased significantly, indicating the centrality of ferroptosis in CaOx crystal-induced renal injury [171]

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Non-steroidal anti-inflammatory drugs (NSAIDs), statins, glucocorticoids and monoclonal antibodies (e.g., targeting IL-6, TNF-, IL-12/23) have been reported to show moderate anti-depressant capacity in patients with somatic disorders (i.e., rheumatoid arthritis, psoriasis) who also had comorbid symptoms of depression [194, 195]

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Its how our bodies regulate weight and each of us is different, each of us is unique, not one is superior to another