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Methods: Two randomized, double-blind (DB), active-controlled trials to evaluate TAF treatment of hepatitis e antigen (HBeAg)-negative (Study GS-US-320-0108) and HBeAg-positive (Study GS-US-320-0110) participants with CHB were conducted over 8 years (384 weeks)

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solution B consisted of 5 l Opti-MEM and 1.5 l (Nrf2), respectively 3 l (CYPOR) of a 10 M siRNA stock solution