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The results of these studies are stimulating the development of better bacterial IMPDH inhibitors to overcome infections (Juvale et al

In 1 small study, women with poorer mean preconception creatinine clearance (CrCl) of 61 mL/min/1.73 m During pregnancy, serum creatinine (not eGFR) should be used, as eGFR will underestimate GFR in pregnancy (57,58)

For example, we do not know whether (i) such an effect is localized to the tissue where the strain is more active or (ii) the rate at which oxidative status markers change differs among strains, depending on their replication rate

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Hydrolysis: Cleavage of the peptide bonds under stressed conditions (heat, pH shifts)