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Data Extraction and Quality Assessment Two investigators (Hu and Song) independently extracted the following data by reviewing the full text of each study: first author, year of publication, Clinical Trial Registration Number (NCT ID), trial duration, patient characteristics, sample size, intervention (type of GLP-1 receptor agonist), comparators, and outcomes of interest

Initially developed as a treatment for type 2 diabetes, the drug gained widespread attention after clinical trials showed it reduced baseline body weight by approximately 10 percent to 15 percent

In both mouse and human cells, the researchers showed that the plant-derived drug caused a variety of cell types, including oral-tissue cells and osteoblasts, or bone-building cells, to grow and differentiate, or divide to form a variety of different cell types

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The quality-and-approval differences between compounded and FDA-approved branded medications are also real

The underlying weight loss is genuinely good for feet over the long term