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Clinical trials conducted in the early 2000s showed modest results, and the compound failed to demonstrate sufficient efficacy to support regulatory approval as a weight-loss medicine
The clearance rate of Dihexa was compared to those of similar nootropic compounds such as piroxicam, verapamil, and 7-ethoxycoumarin [2]
The vitamin C comparison suggests similar discontinuation profile to GHK-Cu where antioxidant effects prove temporary requiring ongoing use while structural improvements may persist partially depending on treatment duration and individual factors
The research is clear that treating underlying issues like depression and anxiety dramatically increase the likelihood of staying healthy long-term
They are often studied together for a synergistic effect
10.1016/j.clbc.2013.10.013 124 MackeyJ
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