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Some Phase I reactions produce electrophiles or free radicals that must be rapidly neutralized through glutathione and other Phase II pathways

It ensures that the body can mount a swift response to infections

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Repeated administration of paracetamol at 0.5 g/kg led to a slight increase in hepatic glutathione, contrasting with acute treatments

In a double-blind, placebo-controlled trial in 11 smokers and 13 nonsmokers given -tocopherol and -tocopherol that was labeled with deuterium, supplementation with vitamin C reduced the rate of vitamin E loss in plasma, likely by regenerating tocopheryl radicals back to nonoxidized forms (22)

Glutathione is a naturally occurring antioxidant found in your body, crucial for detoxifying cells , protecting against damage from toxins, and promoting healthy skin