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Furthermore, bacteria within biofilms exhibit increased gene expression for resistance factors, such as those for antibiotics (e.g., mecA in S

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The primary antibodies used for these experiments were APC-anti-human-CD107a (H4A3), APC-anti-human CD56 (HCD56), PE-anti-human NKG2D (1D11), BV421-anti-mouse CD3 (17A2), APC-anti-mouse NCR1 (29A1.4), APC-anti-mouse CD4 (GK1.5), APC-anti-mouse CD8 (53-6.7) and FITC-anti-mouse CD8 (53-6.7), all from BioLegend

2 Major invasive fungal pathogens and their drug resistance status Fungi represent a major biological kingdom with an extensive evolutionary history, comprising an estimated global diversity of over 5 million species, among which more than one million have been formally identified (Schueffler and Anke, 2014