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GLP-1 receptor agonists are a class of medications originally developed for type 2 diabetes management

Much of the available human evidence is observational, secondary, or exploratory in nature, and many studies were not specifically designed to distinguish sensory function, hedonic liking, motivational wanting, and broader dietary behaviour

Additionally, individuals with a history of failed weight loss attempts, bariatric surgery consideration, or polycystic ovary syndrome often meet clinical criteria

Brain cells derived from Alzheimers disease patients have multiple specific innate abnormalities in energy metabolism

Multiple trials are investigating the effects of GLP-1 RAs on HF