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Het is een veelgebruikte stof geworden in experimenteel en regeneratief onderzoek vanwege de interactie met celherstel- en signaalroutes

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Des-IGF-1 affects glutamate receptor AMPAR binding protein (GRIP), N-ethylmaleimide-sensitive fusion protein (NSF), stargazin, and proteins that interact with C-kinase-1, which influence AMPA receptor anchoring, surface translocation, and synaptic targeting [72]