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Similarly, the association between obesity with cardiovascular disease (CVD), and cognitive decline, in older adults is not definitive

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W., Guarnera, E., Tee, W

Cardiovascular assessment may be performed as clinically indicated for patients on weight management medications, particularly those with existing cardiovascular risk factors

Biol Trace Elem Res 2017;176:5663

If your mood changes noticeably after starting semaglutide or increasing your dose, that is important information your provider needs to help decide whether to adjust your treatment or look for other support