GLP-1 receptors are expressed on up to 70% cerebral arterioles [18] and endothelial cells, and experimental models demonstrate that GLP-1 signaling promotes arteriolar vasodilation, improved endothelial nitric oxide signaling, and angiogenic pathways such as VEGF upregulation, all of which enhance nutrient and oxygen delivery to metabolically active brain regions [13,14]
New England Journal of Medicine , 388(22), 20152027.
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Because GLP-1 also has potential anti-inflammatory properties, it can contribute to a healthier gut lining, thus preventing gastrointestinal problems in the long term
Start your intake How GLP-1 Works Without Breaking Your Budget GLP-1 receptor agonists function by slowing gastric emptying and increasing satiety signals to the brain's appetite centers
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