It most commonly affects areas where skin touches skin, including: The neck (especially the back or sides) Armpits Groin Under the breasts Inner thighs Occasionally, the elbows, knees, or knuckles The texture change is often just as noticeable as the colour change
Cagrilintide monotherapy for treatment of obesity In a 26-week phase 2 trial (n=706, 62 Percentage women, mean age 52 years), cagrilintide was evaluated in 5 groups of subjects receiving 0.3, 0.6, 1.2, 2.4, and 4.5 mg/week as treatment for obesity in comparison with liraglutide 3.0 mg/day, and placebo (table 1) [9]
In 2007, the first single nucleotide polymorphism (SNP) linking high BMI to the fat mass and obesity-related (FTO) gene was found (19)
54 Estimated Glomerular Filtration Rate (eGFR) The estimated glomerular filtration rate (eGFR) test measures how well the kidneys are filtering and excreting certain substances in the blood (eg, creatinine or cystatin C)
doi: 10.1186/s12967-020-02318-8 42 WinklerRKosanC
Maura D, Rahme LG