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Eligible patients aged 18 years or older with type 2 diabetes and HbA1c levels of 7.0 to10.5% (53.0 to 91.0 mmol/mol) on metformin monotherapy from 194 hospitals, clinical institutions or private practices in 16 countries were enrolled

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Whether through intrinsic resistance or acquired resistance following treatment, target cells can employ multiple distinct mechanisms to evade the cytotoxic effects of ADCs, leading to cancer treatment failure

PubMed Simon, J.A., Kingsberg, S.A., Portman, D.J., Lucas, J., Jordan, R., Clayton, A.H., & Shifren, J.L