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[36] This degradation process releases the drug payload specifically into cancerous or tumorous tissue, leveraging the significant difference in redox potential between the oxidizing extracellular environment and the reducing intracellular cytosol

The activation of transcription factors like nuclear factor kappa B (NF-B) and activator protein-1 (AP-1) by ROS is particularly significant in cancer

The large intestine (from the cecum to anus) was removed and post-fixed with the same fixative

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