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Compared to other anti-obesity medications (e.g., dulaglutide and semaglutide) administered over the same duration, tirzepatide demonstrated a superior reduction in body fat compartments, including total fat mass, VAT, and waist circumference [63]

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jr PPO1-wt was incubated for different periods of time to check if there is a time dependent inactivation due to the presence of SDS (Table S8)