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Evidence suggests that neuronal mitochondria in the AD brain exhibit fewer cristae and a condensed, darker matrix, characterized by increased fission and diminished fusion ( The association of beta-Amyloid with mitochondrial components induces profound ultrastructural changes and oxidative damage, often mediated by disruptions in AMP-activated protein kinase (AMPK) pathways (Figure 1)

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He took excellent care of me, asked all the right questions before the procedure, and thoroughly prepared me for what to expect both during recovery and afterward