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10.1111/j.1460-9568.2008.06166.x Eur

Molecular Probes, Eugene, OR, USA) dyes live cells while bis(1,3dibutylbarbituric acid) trimethine oxonol (DiBAC

6 They activate mitogen-activated protein kinase (MAPK) pathways that induce key regulators in late G1 phase such as Cyclin Ds and cyclin-dependent-kinases 4/6 (CDKs), which have a critical role in the control of the G1/S transition and the commitment to DNA replication

A systematic approach alternating between different abdominal quadrants, thighs, and upper arms ensures no single site receives repeated injections within 24-48 hours

The intent-to-treat population included all patients who were treated with at least one dose of study medication and provided both a baseline assessment and at least one post-baseline efficacy result