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A 2025 meta-analysis examining over 142,000 participants found that tirzepatide produced significantly greater weight loss than semaglutide, an average of 4.23% more body weight lost

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Laboratory results point to changes in interleukin expression and modulation of chemokine signals, which appear to correlate with reduced infiltration of certain immune cells

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Avoid strong odors, spicy foods, and greasy meals that can trigger symptoms

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