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GLP-1R activation and artery wall function GLP-1 has pleiotropic effects on the cardiovascular system

The amino acid sequence of liraglutide is 97% homologous to GLP-1, and the lysine at position 26 is connected to a 16-carbon fatty acid, which not only enhances the resistance of liraglutide to the degradation of DPP-4, but also provides a slow release effect, extending the half-life to 10~14 h

Tirzepatide SURMOUNT and SURPASS trial results Tirzepatide has been studied extensively in the SURMOUNT program for weight management and SURPASS program for type 2 diabetes

Sensory neurons that detect stretch and nutrients in the digestive system

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