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Tirzepatide 15 mg (the highest available dose) was the most effective in lowering A1c versus placebo (mean difference [MD], 2%, 95% CI -2.16 to -1.84), followed by tirzepatide 10 mg (MD -1.86%, 95% CI -2.02 to -1.84) and semaglutide 2 mg (MD, 95% CI -1.62%, -1.96 to -1.28)
It is also licensed for weight management in adolescents aged 12-17 years with obesity and body weight above 60 kg
The relationship between oxidative stress, selenium, and cumulative risk in metabolic syndrome
Equally important, lifestyle support should continue even when medication access is stable