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This does not change the semaglutide or tirzepatide dose itself, but it affects when other medications should be taken relative to the peptide injection
Sergey Terushkin, MD, FACS Many patients compare themselves to dramatic before-and-after photos online
Both have different doses and titration schedules
The study also found that 99.2% of patients achieved at least 5% weight loss, 93.9% lost 10% or more, and nearly half (47.8%) achieved 20% or more body weight loss
This dual mechanism is why tirzepatide doses start at 2.5 mg while semaglutide starts at 0.25 mg
Results vary based on starting weight, dose escalation, nutrition habits, physical activity, and consistency with treatment
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