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therefore improvement of insulin resistance, or insulin sensitivity, may have therapeutic potentiality in preventing the progression of NAFLD.96 Insulin sensitizers have been tried.97 Exendin-4 is a 39 amino acid agonist of the glucagon-like peptide 1 (GLP-1) receptor

The wide array of activities associated with GHS-R1a activation is explained, in part, via the interaction of the receptor with other GPCR

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However, genetics alone do not guarantee outcomes