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All in all, the different pathways involved in GSH homeostasis are an indication of the complex dynamic and quick turn over of this tripeptide, and provide clues for potential targets for a GSH-depleting, ferroptosis-inducing strategy

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Sleep (2018)

However, current evidence is mainly derived from preclinical studies, and further investigations, particularly rigorous clinical trials in humans, are necessary to clarify the mechanisms involved and to evaluate their efficacy and safety in patients with cutaneous melanoma

Experts Cassie Moore, PhD is an Assistant Professor of Division of Behavioral Biology, Psychiatry and Behavioral Sciences at Johns Hopkins University School of Medicine

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