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Colchicine has been shown to induce reversible malabsorption of vitamin B12, apparently by altering the function of ileal mucosa

Based on these experimental data, intraperitoneal injection led to observable behavioral improvements within 24 hours, while oral administration required several days of accumulation to reach a stable and significant effect

The activation promotes angiogenesis and improves blood flow to damaged, hypovascular tissues (tendons and ligaments)

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