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Common side effects reported with retatrutide include: Nausea, vomiting, and diarrhoea (most frequent, particularly during dose escalation) Decreased appetite Constipation Injection site reactions Mild increases in heart rate Cagrilintide has demonstrated a generally well-tolerated profile, with gastrointestinal symptoms also being the most commonly reported adverse effects

Practical administration advice: If you miss a dose, take it as soon as possible within 5 days after the missed dose

Zhang K, He M, Wang F, Zhang H, Li Y, Yang J et al

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Thirty-six months later, they were shown to be safe, without signs of tumor formation or other adverse side effects