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Yes, the PlexusDx Precision Peptide Genetic Test identifies variants in your GLP1R, GIPR, FTO, and MC4R genes that influence how you respond to semaglutide and tirzepatide

However, this is unlikely to reflect the physiological situation under which the central GLP1 system evolved, and thus, it will be important to determine whether PPG neurons are indeed only a secondary satiation system under more naturalistic feeding conditions in rodents and humans

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And that's not just weight loss that's also an independent effect of GLP-1

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