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Explanation Isotretinoin has the effect of promoting skin turnover and improving post-acne hyperpigmentation

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It also normalized levels of neurotransmitters and hormones in various stress conditions (leading some to propose it has a balancing effect on the brain-gut axis )

But if any of the following apply to you, your glutathione needs are likely elevated: Chronic digestive issues (IBS, IBD, SIBO, Candida overgrowth) Chronic fatigue or poor sleep Mood symptoms: anxiety, depression, brain fog Chronic infections or a history of immune dysfunction Significant toxin or alcohol exposure Heavy training or high athletic output Metabolic issues (obesity, blood sugar dysregulation) Neurological symptoms (tinnitus, cognitive decline) Older age

This is because the underlying dysfunction is sadly seldom addressed - at the root of these conditions there is always leaky gut and systemic inflammation