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Greenish or brownish discoloration indicates copper oxidation and peptide bond cleavage, meaning the coordination complex has dissociated and the compound is no longer biologically active

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Supplementation with cysteine has been shown to lessen the drop in thyroid hormones associated with oxidative stress

However, this study required high doses of L-carnitine paired with insulin-elevating carbohydrates over 24 weeks, which may not be practical for most athletes