Requisite omega-3 HUFA biomarker thresholds for preventing murine lupus flaring
11 Although low concentrations of PPA may be beneficial, humans with impairments in PPA metabolism (that is, propionic or methymalonic acidemia, holocarboxylase, biotinidase or B12 deficiency, valproate or ethanol exposure) exhibit neurodevelopmental conditions with behavioral and biochemical similarities to ASD
NAD + also plays an important role in DNA repair, serving as a substrate for poly-(ADP-ribose) polymerase (PARP) enzymes that are involved in the response to DNA damage (127130)
The use of the Ca 2+ -sensitive receptor (CaSR) inhibitor NPS-2143 can block the carnitine-induced increase in the cytoplasmic Ca 2+ concentration, indicating that carnitine-induced Ca 2+ mobilization is mediated by the activation of CaSR [119]
BMJ Case Rep doi:10.1136/bcr-2015-210727 Kim H, Chu K, Jung KH, Lee ST, Kim JM, Lee SK (2012) Acquired encephalopathy associated with carnitine deficiency after cefditoren pivoxil administration
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