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in the European Journal of Endocrinology.

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Eighty-nine patients were previously included in the study by Le Guellec et al

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198,199 SHANK genes, including SHANK1, SHANK2 and SHANK3 , directly encode the proteins in the postsynaptic scaffolding protein family, which are located in the PSDs of excitatory synapses

Treatment of ELT3 cells with the NAMPT inhibitor FK866 significantly elevated OS levels, inducing mitochondrial dysfunction and DNA damage