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GLP-1 medications (semaglutide, tirzepatide, etc.) have helped many people reach healthier weights, but relying on them indefinitely can come with trade-offs: loss of muscle, facial volume changes (the so-called Ozempic face), sagging or loss of gluteal fullness, and difficulty maintaining tone when meds are reduced or stopped

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CLINICAL RELEVANCE Evidence that glutathione is involved in the metabolic disturbances which underlie diabetes, obesity, insulin resistance, and the metabolic syndrome continues to grow as well