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In the MitoPark PD mice, in which mitochondrial function is impaired in the dopaminergic neurons, PT320, a sustained release formulation of the GLP-1RA exenatide, reduced ROS production and improved tyrosine hydroxylase expression

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31,32 In diabetic peripheral neuropathy (DPN), macrophages infiltrate to initiate repairment on nerve injury, with more cytokine and chemokine released

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